Response Monitoring with [(18)F]FLT PET and Diffusion-Weighted MRI After Cytotoxic 5-FU Treatment in an Experimental Rat Model for Colorectal Liver Metastases

PURPOSE: The aim of the study was to investigate the potential of diffusion-weighted magnetic resonance imaging (DW-MRI) and 3′-dexoy-3′-[(18)F]fluorothymidine ([(18)F]FLT) positron emission tomography (PET) as early biomarkers of treatment response of 5-fluorouracil (5-FU) in a syngeneic rat model...

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Publicado en:Mol Imaging Biol
Autores principales: Heskamp, Sandra, Heijmen, Linda, Gerrits, Danny, Molkenboer-Kuenen, Janneke D. M., ter Voert, Edwin G. W., Heinzmann, Kathrin, Honess, Davina J., Smith, Donna-Michelle, Griffiths, John R., Doblas, Sabrina, Sinkus, Ralph, Laverman, Peter, Oyen, Wim J. G., Heerschap, Arend, Boerman, Otto C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2016
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498638/
https://ncbi.nlm.nih.gov/pubmed/27798786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-016-1021-2
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