Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies

Despite several clinical trials implemented, no antiviral drug could demonstrate efficacy against Ebola virus. In non-human primates, early initiation of polymerase inhibitors favipiravir and remdesivir improves survival, but whether they could be effective in patients is unknown. Here we analyze th...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Madelain, Vincent, Baize, Sylvain, Jacquot, Frédéric, Reynard, Stéphanie, Fizet, Alexandra, Barron, Stephane, Solas, Caroline, Lacarelle, Bruno, Carbonnelle, Caroline, Mentré, France, Raoul, Hervé, de Lamballerie, Xavier, Guedj, Jérémie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167368/
https://ncbi.nlm.nih.gov/pubmed/30275474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06215-z
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