Placebo‐Controlled Randomized Trial of an Intestinal Bile Salt Transport Inhibitor for Pruritus in Alagille Syndrome

Medically refractory, severe, cholestasis‐induced pruritus in Alagille syndrome may be improved by surgical interruption of the enterohepatic circulation. This multicenter trial (NCT02057692) tested the hypothesis that the intestinal bile acid transport inhibitor maralixibat would similarly reduce p...

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Detalhes bibliográficos
Publicado no:Hepatol Commun
Main Authors: Shneider, Benjamin L., Spino, Cathie, Kamath, Binita M., Magee, John C., Bass, Lee M., Setchell, Kenneth D., Miethke, Alexander, Molleston, Jean P., Mack, Cara L., Squires, Robert H., Murray, Karen F., Loomes, Kathleen M., Rosenthal, Philip, Karpen, Saul J., Leung, Daniel H., Guthery, Stephen L., Thomas, Danny, Sherker, Averell H., Sokol, Ronald J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167076/
https://ncbi.nlm.nih.gov/pubmed/30288474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1244
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