The Relative Biological Effect of Spread-Out Bragg Peak Protons in Sensitive and Resistant Tumor Cells

PURPOSE: Variations in the radiosensitivity of tumor cells within and between tumors impact tumor response to radiation, including the dose required to achieve permanent local tumor control. The increased expression of DNA-PKcs, a key component of a major DNA damage repair pathway in tumors treated...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Part Ther
Hauptverfasser: Lin, Yu-Fen, Chen, Benjamin P., Li, Wende, Perko, Zoltan, Wang, Yi, Testa, Mauro, Schneider, Robert, Lu, Hsaio-Ming, Gerweck, Leo E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Particle Therapy Co-operative Group 2018
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167011/
https://ncbi.nlm.nih.gov/pubmed/30283809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14338/IJPT-17-00025.1
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