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The Relative Biological Effect of Spread-Out Bragg Peak Protons in Sensitive and Resistant Tumor Cells

PURPOSE: Variations in the radiosensitivity of tumor cells within and between tumors impact tumor response to radiation, including the dose required to achieve permanent local tumor control. The increased expression of DNA-PKcs, a key component of a major DNA damage repair pathway in tumors treated...

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Detalhes bibliográficos
Publicado no:Int J Part Ther
Main Authors: Lin, Yu-Fen, Chen, Benjamin P., Li, Wende, Perko, Zoltan, Wang, Yi, Testa, Mauro, Schneider, Robert, Lu, Hsaio-Ming, Gerweck, Leo E.
Formato: Artigo
Idioma:Inglês
Publicado em: The Particle Therapy Co-operative Group 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6167011/
https://ncbi.nlm.nih.gov/pubmed/30283809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14338/IJPT-17-00025.1
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