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Structural conditions on complex networks for the Michaelis–Menten input–output response
The Michaelis–Menten (MM) fundamental formula describes how the rate of enzyme catalysis depends on substrate concentration. The familiar hyperbolic relationship was derived by timescale separation for a network of three reactions. The same formula has subsequently been found to describe steady-stat...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6166846/ https://ncbi.nlm.nih.gov/pubmed/30194237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808053115 |
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