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Structural conditions on complex networks for the Michaelis–Menten input–output response

The Michaelis–Menten (MM) fundamental formula describes how the rate of enzyme catalysis depends on substrate concentration. The familiar hyperbolic relationship was derived by timescale separation for a network of three reactions. The same formula has subsequently been found to describe steady-stat...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wong, Felix, Dutta, Annwesha, Chowdhury, Debashish, Gunawardena, Jeremy
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166846/
https://ncbi.nlm.nih.gov/pubmed/30194237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808053115
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