Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis

The Xenopus laevis embryo has been subjected to almost saturating screens for molecules specifically expressed in dorsal Spemann organizer tissue. In this study, we performed high-throughput RNA sequencing of ectodermal explants, called animal caps, which normally give rise to epidermis. We analyzed...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Ding, Yi, Colozza, Gabriele, Sosa, Eric A., Moriyama, Yuki, Rundle, Samantha, Salwinski, Lukasz, De Robertis, Edward M.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166843/
https://ncbi.nlm.nih.gov/pubmed/30209221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812117115
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