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Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis

The Xenopus laevis embryo has been subjected to almost saturating screens for molecules specifically expressed in dorsal Spemann organizer tissue. In this study, we performed high-throughput RNA sequencing of ectodermal explants, called animal caps, which normally give rise to epidermis. We analyzed...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Ding, Yi, Colozza, Gabriele, Sosa, Eric A., Moriyama, Yuki, Rundle, Samantha, Salwinski, Lukasz, De Robertis, Edward M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166843/
https://ncbi.nlm.nih.gov/pubmed/30209221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1812117115
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