Function and crystal structure of the dimeric P-loop ATPase CFD1 coordinating an exposed [4Fe-4S] cluster for transfer to apoproteins

Maturation of iron-sulfur (Fe-S) proteins in eukaryotes requires complex machineries in mitochondria and cytosol. Initially, Fe-S clusters are assembled on dedicated scaffold proteins and then are trafficked to target apoproteins. Within the cytosolic Fe-S protein assembly (CIA) machinery, the conse...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Stehling, Oliver, Jeoung, Jae-Hun, Freibert, Sven A., Paul, Viktoria D., Bänfer, Sebastian, Niggemeyer, Brigitte, Rösser, Ralf, Dobbek, Holger, Lill, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166825/
https://ncbi.nlm.nih.gov/pubmed/30201724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807762115
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