Deconvolution of pro- and antiviral genomic responses in Zika virus-infected and bystander macrophages

Genome-wide investigations of host–pathogen interactions are often limited by analyses of mixed populations of infected and uninfected cells, which lower sensitivity and accuracy. To overcome these obstacles and identify key mechanisms by which Zika virus (ZIKV) manipulates host responses, we develo...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Carlin, Aaron F., Vizcarra, Edward A., Branche, Emilie, Viramontes, Karla M., Suarez-Amaran, Lester, Ley, Klaus, Heinz, Sven, Benner, Christopher, Shresta, Sujan, Glass, Christopher K.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166801/
https://ncbi.nlm.nih.gov/pubmed/30206152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807690115
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