Deconvolution of pro- and antiviral genomic responses in Zika virus-infected and bystander macrophages

Genome-wide investigations of host–pathogen interactions are often limited by analyses of mixed populations of infected and uninfected cells, which lower sensitivity and accuracy. To overcome these obstacles and identify key mechanisms by which Zika virus (ZIKV) manipulates host responses, we develo...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Carlin, Aaron F., Vizcarra, Edward A., Branche, Emilie, Viramontes, Karla M., Suarez-Amaran, Lester, Ley, Klaus, Heinz, Sven, Benner, Christopher, Shresta, Sujan, Glass, Christopher K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166801/
https://ncbi.nlm.nih.gov/pubmed/30206152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807690115
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