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Superoxide dismutase activity confers (p)ppGpp-mediated antibiotic tolerance to stationary-phase Pseudomonas aeruginosa

Metabolically quiescent bacteria represent a large proportion of those in natural and host environments, and they are often refractory to antibiotic treatment. Such drug tolerance is also observed in the laboratory during stationary phase, when bacteria face stress and starvation-induced growth arre...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Martins, Dorival, McKay, Geoffrey, Sampathkumar, Gowthami, Khakimova, Malika, English, Ann M., Nguyen, Dao
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166797/
https://ncbi.nlm.nih.gov/pubmed/30201715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804525115
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