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Superoxide dismutase activity confers (p)ppGpp-mediated antibiotic tolerance to stationary-phase Pseudomonas aeruginosa

Metabolically quiescent bacteria represent a large proportion of those in natural and host environments, and they are often refractory to antibiotic treatment. Such drug tolerance is also observed in the laboratory during stationary phase, when bacteria face stress and starvation-induced growth arre...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Martins, Dorival, McKay, Geoffrey, Sampathkumar, Gowthami, Khakimova, Malika, English, Ann M., Nguyen, Dao
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166797/
https://ncbi.nlm.nih.gov/pubmed/30201715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1804525115
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