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In vitro Enzymatic Assays of Histone Decrotonylation on Recombinant Histones

Class I histone deacetylases (HDACs) are efficient histone decrotonylases, broadening the enzymatic spectrum of these important (epi-)genome regulators and drug targets. Here, we describe an in vitro approach to assaying class I HDACs with different acyl-histone substrates, including crotonylated hi...

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Detalhes bibliográficos
Publicado no:Bio Protoc
Main Authors: Fellows, Rachel, Varga-Weisz, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Bio-Protocol 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166789/
https://ncbi.nlm.nih.gov/pubmed/30283810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21769/BioProtoc.2924
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