SCA8 RAN polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F

Spinocerebellar ataxia type 8 (SCA8) is caused by a bidirectionally transcribed CTG·CAG expansion that results in the in vivo accumulation of CUG RNA foci, an ATG‐initiated polyGln and a polyAla protein expressed by repeat‐associated non‐ATG (RAN) translation. Although RAN proteins have been reporte...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Ayhan, Fatma, Perez, Barbara A, Shorrock, Hannah K, Zu, Tao, Banez‐Coronel, Monica, Reid, Tammy, Furuya, Hirokazu, Clark, H Brent, Troncoso, Juan C, Ross, Christopher A, Subramony, SH, Ashizawa, Tetsuo, Wang, Eric T, Yachnis, Anthony T, Ranum, Laura PW
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6166133/
https://ncbi.nlm.nih.gov/pubmed/30206144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899023
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados