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Clinicopathologic Significance of VHL Gene Alteration in Clear-Cell Renal Cell Carcinoma: An Updated Meta-Analysis and Review

The von Hippel-Lindau (VHL) gene is inactivated frequently in sporadic clear-cell renal cell carcinomas (ccRCCs) by genetic alteration (mutation, loss of heterozygosity, or promoter hypermethylation). However, the pathological or prognostic significance of VHL gene alteration has not been well defin...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Kim, Hyeong Su, Kim, Jung Han, Jang, Hyun Joo, Han, Boram, Zang, Dae Young
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6165550/
https://ncbi.nlm.nih.gov/pubmed/30149673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19092529
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