Inhibition of Homophilic Interactions and Ligand Binding of the Receptor for Advanced Glycation End Products by Heparin and Heparin-Related Carbohydrate Structures

Background: Heparin and heparin-related sulphated carbohydrates inhibit ligand binding of the receptor for advanced glycation end products (RAGE). Here, we have studied the ability of heparin to inhibit homophilic interactions of RAGE in living cells and studied how heparin related structures interf...

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Publicado en:Medicines (Basel)
Main Authors: Rouhiainen, Ari, Nykänen, Niko-Petteri, Kuja-Panula, Juha, Vanttola, Päivi, Huttunen, Henri J., Rauvala, Heikki
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6165534/
https://ncbi.nlm.nih.gov/pubmed/30061484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medicines5030079
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