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Inhibition of Homophilic Interactions and Ligand Binding of the Receptor for Advanced Glycation End Products by Heparin and Heparin-Related Carbohydrate Structures

Background: Heparin and heparin-related sulphated carbohydrates inhibit ligand binding of the receptor for advanced glycation end products (RAGE). Here, we have studied the ability of heparin to inhibit homophilic interactions of RAGE in living cells and studied how heparin related structures interf...

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Detalhes bibliográficos
Publicado no:Medicines (Basel)
Main Authors: Rouhiainen, Ari, Nykänen, Niko-Petteri, Kuja-Panula, Juha, Vanttola, Päivi, Huttunen, Henri J., Rauvala, Heikki
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6165534/
https://ncbi.nlm.nih.gov/pubmed/30061484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medicines5030079
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