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Inhibition of Homophilic Interactions and Ligand Binding of the Receptor for Advanced Glycation End Products by Heparin and Heparin-Related Carbohydrate Structures

Background: Heparin and heparin-related sulphated carbohydrates inhibit ligand binding of the receptor for advanced glycation end products (RAGE). Here, we have studied the ability of heparin to inhibit homophilic interactions of RAGE in living cells and studied how heparin related structures interf...

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Bibliografski detalji
Izdano u:Medicines (Basel)
Glavni autori: Rouhiainen, Ari, Nykänen, Niko-Petteri, Kuja-Panula, Juha, Vanttola, Päivi, Huttunen, Henri J., Rauvala, Heikki
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6165534/
https://ncbi.nlm.nih.gov/pubmed/30061484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/medicines5030079
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