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Uremic Toxins Activates Na/K-ATPase Oxidant Amplification Loop Causing Phenotypic Changes in Adipocytes in In Vitro Models

Background: Oxidant stress plays a key role in the development of chronic kidney disease (CKD). Experimental CKD leads to accumulation of uremic toxins (UT) in the circulation resulting in increased ROS production, which in turn, is known to activate the Na/K-ATPase/ROS amplification loop. Studies i...

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書目詳細資料
發表在:Int J Mol Sci
Main Authors: Bartlett, David E., Miller, Richard B., Thiesfeldt, Scott, Lakhani, Hari Vishal, Khanal, Tilak, D. Pratt, Rebecca, Cottrill, Cameron L., Klug, Rebecca L., Adkins, Nathaniel Seth, Bown, Paul C., Nease, D. Blaine, Shapiro, Joseph I., Sodhi, Komal
格式: Artigo
語言:Inglês
出版: MDPI 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6164729/
https://ncbi.nlm.nih.gov/pubmed/30201874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19092685
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