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Platycodon grandiflorum Saponins Ameliorate Cisplatin-Induced Acute Nephrotoxicity through the NF-κB-Mediated Inflammation and PI3K/Akt/Apoptosis Signaling Pathways

Although cisplatin is a potent chemotherapeutic agent against cancers, its clinical application is seriously limited by its severe side effects of nephrotoxicity. Previous studies reported that saponins isolated from the roots of Platycodon grandiflorum (PGS) exerted protective effects in various an...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nutrients
Egile Nagusiak: Zhang, Weizhe, Hou, Jingang, Yan, Xiaotong, Leng, Jing, Li, Rongyan, Zhang, Jing, Xing, Jingjing, Chen, Chen, Wang, Zi, Li, Wei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6164643/
https://ncbi.nlm.nih.gov/pubmed/30235825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu10091328
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