Dissociation of Fatty Liver and Insulin Resistance in I148M PNPLA3 Carriers: Differences in Diacylglycerol (DAG) FA18:1 Lipid Species as a Possible Explanation

Fatty liver is tightly associated with insulin resistance and the development of type 2 diabetes. I148M variant in patatin-like phospholipase domain-containing protein 3 (PNPLA3) gene is associated with high liver fat but normal insulin sensitivity. The underlying mechanism of the disassociation bet...

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Publicat a:Nutrients
Autors principals: Franko, Andras, Merkel, Dietrich, Kovarova, Marketa, Hoene, Miriam, Jaghutriz, Benjamin A., Heni, Martin, Königsrainer, Alfred, Papan, Cyrus, Lehr, Stefan, Häring, Hans-Ulrich, Peter, Andreas
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6164484/
https://ncbi.nlm.nih.gov/pubmed/30227635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu10091314
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