Inhibition of Wnt3a/FOXM1/β-Catenin Axis and Activation of GSK3β and Caspases are Critically Involved in Apoptotic Effect of Moracin D in Breast Cancers

Although Moracin D derived from Morus alba was known to have anti-inflammatory and antioxidant activities, the underlying antitumor mechanism of Moracin D has not been unveiled thus far. Thus, in the recent study, the apoptotic mechanism of Moracin D was elucidated in breast cancer cells. Herein, Mo...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Hwang, Sung Min, Lee, Hyo-Jung, Jung, Ji Hoon, Sim, Deok Yong, Hwang, Jisung, Park, Ji Eon, Shim, Bum Sang, Kim, Sung-Hoon
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6164368/
https://ncbi.nlm.nih.gov/pubmed/30201862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19092681
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