Toward the Synthesis and Improved Biopotential of an N-methylated Analog of a Proline-Rich Cyclic Tetrapeptide from Marine Bacteria

An N-methylated analog of a marine bacteria-derived natural proline-rich tetracyclopeptide was synthesized by coupling the deprotected dipeptide fragments Boc-l-prolyl-l-N-methylleucine-OH and l-prolyl-l-N-methylphenylalanine-OMe. A coupling reaction was accomplished utilizing N,N′-Dicyclohexylcarbo...

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Publicado no:Mar Drugs
Main Authors: Dahiya, Rajiv, Kumar, Suresh, Khokra, Sukhbir Lal, Gupta, Sheeba Varghese, Sutariya, Vijaykumar B., Bhatia, Deepak, Sharma, Ajay, Singh, Shamjeet, Maharaj, Sandeep
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6163976/
https://ncbi.nlm.nih.gov/pubmed/30200225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md16090305
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