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Targeting IKKβ in Cancer: Challenges and Opportunities for the Therapeutic Utilisation of IKKβ Inhibitors

Deregulated NF-κB signalling is implicated in the pathogenesis of numerous human inflammatory disorders and malignancies. Consequently, the NF-κB pathway has attracted attention as an attractive therapeutic target for drug discovery. As the primary, druggable mediator of canonical NF-κB signalling t...

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Publicado no:Cells
Main Authors: Prescott, Jack A., Cook, Simon J.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162708/
https://ncbi.nlm.nih.gov/pubmed/30142927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7090115
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