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Fibrin(ogen) as a Therapeutic Target: Opportunities and Challenges
Fibrinogen is one of the key molecular players in haemostasis. Thrombin-mediated release of fibrinopeptides from fibrinogen converts this soluble protein into a network of fibrin fibres that form a building block for blood clots. Thrombin-activated factor XIII further crosslinks the fibrin fibres an...
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| Publié dans: | Int J Mol Sci |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2021
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8268464/ https://ncbi.nlm.nih.gov/pubmed/34203139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22136916 |
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