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Profiling DNA Methylation Based on Next-Generation Sequencing Approaches: New Insights and Clinical Applications

DNA methylation is an epigenetic modification that plays a pivotal role in regulating gene expression and, consequently, influences a wide variety of biological processes and diseases. The advances in next-generation sequencing technologies allow for genome-wide profiling of methyl marks both at a s...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Barros-Silva, Daniela, Marques, C. Joana, Henrique, Rui, Jerónimo, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162482/
https://ncbi.nlm.nih.gov/pubmed/30142958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9090429
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