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The Application of Next Generation Sequencing in DNA Methylation Analysis

DNA methylation is a major form of epigenetic modification and plays essential roles in physiology and disease processes. In the human genome, about 80% of cytosines in the 56 million CpG sites are methylated to 5-methylcytosines. The methylation pattern of DNA is highly variable among cells types a...

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Detalhes bibliográficos
Main Authors: Zhang, Yingying, Jeltsch, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960863/
https://ncbi.nlm.nih.gov/pubmed/24710012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes1010085
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