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Marfan Syndrome Variability: Investigation of the Roles of Sarcolipin and Calcium as Potential Transregulator of FBN1 Expression

Marfan syndrome (MFS) is an autosomal dominant connective tissue disorder that displays a great clinical variability. Previous work in our laboratory showed that fibrillin-1 (FBN1) messenger RNA (mRNA) expression is a surrogate endpoint for MFS severity. Therefore, an expression quantitative trait l...

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Bibliografiske detaljer
Udgivet i:Genes (Basel)
Main Authors: Benarroch, Louise, Aubart, Mélodie, Gross, Marie-Sylvie, Jacob, Marie-Paule, Arnaud, Pauline, Hanna, Nadine, Jondeau, Guillaume, Boileau, Catherine
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162465/
https://ncbi.nlm.nih.gov/pubmed/30134586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes9090421
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