Antibodies Set Boundaries Limiting Microbial Metabolite Penetration and the Resultant Mammalian Host Response

Although the mammalian microbiota is well contained within the intestine, it profoundly shapes development and metabolism of almost every host organ. We questioned the range and depth of microbial metabolite penetration into the host, and how this is modulated by intestinal immunity. Chemically iden...

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Pubblicato in:Immunity
Autori principali: Uchimura, Yasuhiro, Fuhrer, Tobias, Li, Hai, Lawson, Melissa A., Zimmermann, Michael, Yilmaz, Bahtiyar, Zindel, Joel, Ronchi, Francesca, Sorribas, Marcel, Hapfelmeier, Siegfried, Ganal-Vonarburg, Stephanie C., Gomez de Agüero, Mercedes, McCoy, Kathy D., Sauer, Uwe, Macpherson, Andrew J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162337/
https://ncbi.nlm.nih.gov/pubmed/30193848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.08.004
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