Antibodies Set Boundaries Limiting Microbial Metabolite Penetration and the Resultant Mammalian Host Response

Although the mammalian microbiota is well contained within the intestine, it profoundly shapes development and metabolism of almost every host organ. We questioned the range and depth of microbial metabolite penetration into the host, and how this is modulated by intestinal immunity. Chemically iden...

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Publicat a:Immunity
Autors principals: Uchimura, Yasuhiro, Fuhrer, Tobias, Li, Hai, Lawson, Melissa A., Zimmermann, Michael, Yilmaz, Bahtiyar, Zindel, Joel, Ronchi, Francesca, Sorribas, Marcel, Hapfelmeier, Siegfried, Ganal-Vonarburg, Stephanie C., Gomez de Agüero, Mercedes, McCoy, Kathy D., Sauer, Uwe, Macpherson, Andrew J.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162337/
https://ncbi.nlm.nih.gov/pubmed/30193848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2018.08.004
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