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Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor specificity

The T cell receptor (TCR) repertoire encodes immune exposure history through the dynamic formation of immunological memory. Statistical analysis of repertoire sequencing data has the potential to decode disease associations from large cohorts with measured phenotypes. However, the repertoire perturb...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:eLife
Hauptverfasser: DeWitt, William S, Smith, Anajane, Schoch, Gary, Hansen, John A, Matsen, Frederick A, Bradley, Philip
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162092/
https://ncbi.nlm.nih.gov/pubmed/30152754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38358
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