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Human T cell receptor occurrence patterns encode immune history, genetic background, and receptor specificity

The T cell receptor (TCR) repertoire encodes immune exposure history through the dynamic formation of immunological memory. Statistical analysis of repertoire sequencing data has the potential to decode disease associations from large cohorts with measured phenotypes. However, the repertoire perturb...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: DeWitt, William S, Smith, Anajane, Schoch, Gary, Hansen, John A, Matsen, Frederick A, Bradley, Philip
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162092/
https://ncbi.nlm.nih.gov/pubmed/30152754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38358
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