Host phosphatidic acid phosphatase lipin1 is rate limiting for functional hepatitis C virus replicase complex formation

Hepatitis C virus (HCV) infection constitutes a significant health burden worldwide, because it is a major etiologic agent of chronic liver disease, cirrhosis and hepatocellular carcinoma. HCV replication cycle is closely tied to lipid metabolism and infection by this virus causes profound changes i...

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Udgivet i:PLoS Pathog
Main Authors: Mingorance, Lidia, Castro, Victoria, Ávila-Pérez, Ginés, Calvo, Gema, Rodriguez, María Josefa, Carrascosa, José L., Pérez-del-Pulgar, Sofía, Forns, Xavier, Gastaminza, Pablo
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161900/
https://ncbi.nlm.nih.gov/pubmed/30226904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007284
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