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Inhibition of interleukin-1 receptor-associated kinase 1 (IRAK1) as a therapeutic strategy
Interleukin-1 receptor-associated kinases (IRAK1, IRAK2, IRAK3 [IRAK-M], and IRAK4) are serine-threonine kinases involved in toll-like receptor and interleukin-1 signaling pathways, through which they regulate innate immunity and inflammation. Evidence exists that IRAKs play key roles in the pathoph...
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| Pubblicato in: | Oncotarget |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Impact Journals LLC
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6161786/ https://ncbi.nlm.nih.gov/pubmed/30279971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26058 |
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