Non-classical monocytes as mediators of tissue destruction in arthritis

OBJECTIVES: Bone destruction in rheumatoid arthritis is mediated by osteoclasts (OC), which are derived from precursor cells of the myeloid lineage. The role of the two monocyte subsets, classical monocytes (expressing CD115, Ly6C and CCR2) and non-classical monocytes (which are CD115 positive, but...

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Vydáno v:Ann Rheum Dis
Hlavní autoři: Puchner, Antonia, Saferding, Victoria, Bonelli, Michael, Mikami, Yohei, Hofmann, Melanie, Brunner, Julia S, Caldera, Michael, Goncalves-Alves, Eliana, Binder, Nikolaus B, Fischer, Anita, Simader, Elisabeth, Steiner, Carl-Walter, Leiss, Harald, Hayer, Silvia, Niederreiter, Birgit, Karonitsch, Thomas, Koenders, Marije I, Podesser, Bruno K, O’Shea, John J, Menche, Jörg, Smolen, Josef S, Redlich, Kurt, Blüml, Stephan
Médium: Artigo
Jazyk:Inglês
Vydáno: BMJ Publishing Group 2018
Témata:
Basic and Translational Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161666/
https://ncbi.nlm.nih.gov/pubmed/29959183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2018-213250
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