Non-classical monocytes as mediators of tissue destruction in arthritis

OBJECTIVES: Bone destruction in rheumatoid arthritis is mediated by osteoclasts (OC), which are derived from precursor cells of the myeloid lineage. The role of the two monocyte subsets, classical monocytes (expressing CD115, Ly6C and CCR2) and non-classical monocytes (which are CD115 positive, but...

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Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Puchner, Antonia, Saferding, Victoria, Bonelli, Michael, Mikami, Yohei, Hofmann, Melanie, Brunner, Julia S, Caldera, Michael, Goncalves-Alves, Eliana, Binder, Nikolaus B, Fischer, Anita, Simader, Elisabeth, Steiner, Carl-Walter, Leiss, Harald, Hayer, Silvia, Niederreiter, Birgit, Karonitsch, Thomas, Koenders, Marije I, Podesser, Bruno K, O’Shea, John J, Menche, Jörg, Smolen, Josef S, Redlich, Kurt, Blüml, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Basic and Translational Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161666/
https://ncbi.nlm.nih.gov/pubmed/29959183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2018-213250
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