Effective Knockdown of Gene Expression in Primary Microglia With siRNA and Magnetic Nanoparticles Without Cell Death or Inflammation

Microglia, the resident immune cells of the brain, have multiple functions in physiological and pathological conditions, including Alzheimer’s disease (AD). The use of primary microglial cell cultures has proved to be a valuable tool to study microglial biology under various conditions. However, mor...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Carrillo-Jimenez, Alejandro, Puigdellívol, Mar, Vilalta, Anna, Venero, Jose Luis, Brown, Guy Charles, StGeorge-Hyslop, Peter, Burguillos, Miguel Angel
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161539/
https://ncbi.nlm.nih.gov/pubmed/30297984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00313
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