Effective Knockdown of Gene Expression in Primary Microglia With siRNA and Magnetic Nanoparticles Without Cell Death or Inflammation

Microglia, the resident immune cells of the brain, have multiple functions in physiological and pathological conditions, including Alzheimer’s disease (AD). The use of primary microglial cell cultures has proved to be a valuable tool to study microglial biology under various conditions. However, mor...

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Bibliografiska uppgifter
I publikationen:Front Cell Neurosci
Huvudupphovsmän: Carrillo-Jimenez, Alejandro, Puigdellívol, Mar, Vilalta, Anna, Venero, Jose Luis, Brown, Guy Charles, StGeorge-Hyslop, Peter, Burguillos, Miguel Angel
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2018
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161539/
https://ncbi.nlm.nih.gov/pubmed/30297984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00313
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