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Induction of Contrasuppressor Cells and Loss of Immune Privilege Produced by Corneal Nerve Ablation

PURPOSE: Severing of corneal nerves in preparation of corneal transplantation abolishes immune privilege of subsequent corneal transplants placed into either eye: a phenomenon termed sympathetic loss of immune privilege (SLIP). SLIP is due to the disabling of T regulatory cells (Tregs) by CD11c(+) c...

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Détails bibliographiques
Publié dans:Invest Ophthalmol Vis Sci
Auteurs principaux: Neelam, Sudha, Mellon, Jessamee, Wilkerson, Amber, Niederkorn, Jerry Y.
Format: Artigo
Langue:Inglês
Publié: The Association for Research in Vision and Ophthalmology 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161365/
https://ncbi.nlm.nih.gov/pubmed/30267096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.18-24894
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