Development of Dual Drug Loaded Nanosized Liposomal Formulation by A Reengineered Ethanolic Injection Method and Its Pre-Clinical Pharmacokinetic Studies

Oleanolic acid (OA), which is a natural pentacyclic terpenoid, has been identified for hepato-protective, nephron-protective and cardio-tonic properties. In contrast, doxorubicin (DOX) is a famous anti-cancer drug but its efficacy is a question mark because of its known cardio-toxicity. We developed...

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Dettagli Bibliografici
Pubblicato in:Pharmaceutics
Autori principali: Sarfraz, Muhammad, Afzal, Attia, Yang, Tan, Gai, Yongkang, Raza, Shahid Masood, Khan, Muhammad Waseem, Cheng, Yao, Ma, Xiang, Xiang, Guangya
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6161256/
https://ncbi.nlm.nih.gov/pubmed/30200557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10030151
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