Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity

Background: Cisplatin (CDDP), a widely used chemotherapeutic agent against hepatocellular carcinoma (HCC), faces severe resistance and hepatotoxicity problems which can be alleviated through combination therapy. Purpose: The objective of this study was to develop a pH-dependent calcium carbonate nan...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Khan, Muhammad Waseem, Zhao, Pengxuan, Khan, Asifullah, Raza, Faisal, Raza, Shahid Masood, Sarfraz, Muhammad, Chen, Yan, Li, Minsi, Yang, Tan, Ma, Xiang, Xiang, Guangya
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554709/
https://ncbi.nlm.nih.gov/pubmed/31239661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S196651
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