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Effect of Lipid Additives and Drug on the Rheological Properties of Molten Paraffin Wax, Degree of Surface Drug Coating, and Drug Release in Spray-Congealed Microparticles

Paraffin wax is potentially useful for producing spray-congealed drug-loaded microparticles with sustained-release and taste-masking properties. To date, there is little information about the effects of blending lipids with paraffin wax on the melt viscosity. In addition, drug particles may not be e...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Ouyang, Hongyi, Zheng, Audrey Yi, Heng, Paul Wan Sia, Chan, Lai Wah
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160941/
https://ncbi.nlm.nih.gov/pubmed/29949920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10030075
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