Influence of Hydroxypropyl Methylcellulose on Metronidazole Crystallinity in Spray-Congealed Polyethylene Glycol Microparticles and Its Impact with Various Additives on Metronidazole Release

The purpose of this study was to investigate the effect of a hydrophilic polymer, hydroxypropyl methylcellulose (HPMC), on the crystallinity and drug release of metronidazole (MNZ) in spray-congealed polyethylene glycol (PEG) microparticles and to further modify the drug release using other additive...

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Bibliografiske detaljer
Udgivet i:AAPS PharmSciTech
Main Authors: Oh, Ching Mien, Heng, Paul Wan Sia, Chan, Lai Wah
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4666242/
https://ncbi.nlm.nih.gov/pubmed/25933626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0320-2
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