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Systematic Development of Self-Nanoemulsifying Liquisolid Tablets to Improve the Dissolution and Oral Bioavailability of an Oily Drug, Vitamin K1

The purpose of this study is to improve the dissolution and oral bioavailability of an oily drug, vitamin K1 (VK1) by combination of self-nanoemulsifying and liquisolid technologies. The optimal liquid self-nanoemulsifying drug delivery systems (SNEDDS) formulation including VK1 (oil), mixture of so...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Pharmaceutics
Hauptverfasser: Tong, Yongtao, Wang, Yuli, Yang, Meiyan, Yang, Jiahui, Chen, Lu, Chu, Xiaoyang, Gao, Chunhong, Jin, Qian, Gong, Wei, Gao, Chunsheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160939/
https://ncbi.nlm.nih.gov/pubmed/30021949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10030096
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