Systematic Development of Self-Nanoemulsifying Liquisolid Tablets to Improve the Dissolution and Oral Bioavailability of an Oily Drug, Vitamin K1

The purpose of this study is to improve the dissolution and oral bioavailability of an oily drug, vitamin K1 (VK1) by combination of self-nanoemulsifying and liquisolid technologies. The optimal liquid self-nanoemulsifying drug delivery systems (SNEDDS) formulation including VK1 (oil), mixture of so...

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Vydáno v:Pharmaceutics
Hlavní autoři: Tong, Yongtao, Wang, Yuli, Yang, Meiyan, Yang, Jiahui, Chen, Lu, Chu, Xiaoyang, Gao, Chunhong, Jin, Qian, Gong, Wei, Gao, Chunsheng
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160939/
https://ncbi.nlm.nih.gov/pubmed/30021949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics10030096
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