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Generation of MicroRNA-34 Sponges and Tough Decoys for the Heart: Developments and Challenges

Heart failure (HF) is a debilitating and deadly chronic disease, with almost 50% of patients with HF dying within 5 years of diagnosis. With limited effective therapies to treat or cure HF, new therapies are greatly needed. microRNAs (miRNAs) are small non-coding RNA molecules that are powerful regu...

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Detalles Bibliográficos
Publicado en:Front Pharmacol
Main Authors: Bernardo, Bianca C., Gregorevic, Paul, Ritchie, Rebecca H., McMullen, Julie R.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160554/
https://ncbi.nlm.nih.gov/pubmed/30298011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01090
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