Structural insights into modulation and selectivity of transsynaptic neurexin–LRRTM interaction

Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) function as postsynaptic organizers that induce excitatory synapses. Neurexins (Nrxns) and heparan sulfate proteoglycans have been identified as presynaptic ligands for LRRTMs. Specifically, LRRTM1 and LRRTM2 bind to the Nrxn splice varian...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yamagata, Atsushi, Goto-Ito, Sakurako, Sato, Yusuke, Shiroshima, Tomoko, Maeda, Asami, Watanabe, Masahiko, Saitoh, Takashi, Maenaka, Katsumi, Terada, Tohru, Yoshida, Tomoyuki, Uemura, Takeshi, Fukai, Shuya
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160412/
https://ncbi.nlm.nih.gov/pubmed/30262834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06333-8
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