Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice

Neuroligin 3 (NLGN3) and neurexins (NRXNs) constitute a canonical transsynaptic cell-adhesion pair, which has been implicated in autism. In autism spectrum disorder (ASD) development of sociality can be impaired. However, the molecular mechanism underlying NLGN3-mediated social development is unclea...

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Publicat a:Nat Commun
Autors principals: Yoshida, Tomoyuki, Yamagata, Atsushi, Imai, Ayako, Kim, Juhyon, Izumi, Hironori, Nakashima, Shogo, Shiroshima, Tomoko, Maeda, Asami, Iwasawa-Okamoto, Shiho, Azechi, Kenji, Osaka, Fumina, Saitoh, Takashi, Maenaka, Katsumi, Shimada, Takashi, Fukata, Yuko, Fukata, Masaki, Matsumoto, Jumpei, Nishijo, Hisao, Takao, Keizo, Tanaka, Shinji, Okabe, Shigeo, Tabuchi, Katsuhiko, Uemura, Takeshi, Mishina, Masayoshi, Mori, Hisashi, Fukai, Shuya
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7988105/
https://ncbi.nlm.nih.gov/pubmed/33758193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22059-6
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