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Effects of ABCB1 rs1045642 polymorphisms on the efficacy and safety of amlodipine therapy in Caucasian patients with stage I–II hypertension

PURPOSE: The aim of this study was to determine the impact of ABCB1 (MDR1) rs1045642 polymorphisms on the efficacy and safety of amlodipine in Caucasian patients. PATIENTS AND METHODS: The 12-week study included 100 patients. Patients with the newly diagnosed stage I–II hypertension (HT) were recrui...

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Dettagli Bibliografici
Pubblicato in:Pharmgenomics Pers Med
Autori principali: Sychev, Dmitry, Shikh, Nadezhda, Morozova, Tatiana, Grishina, Elena, Ryzhikova, Kristina, Malova, Elena
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159808/
https://ncbi.nlm.nih.gov/pubmed/30288082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/PGPM.S158401
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