Laminin drives survival signals to promote a contractile smooth muscle phenotype and airway hyperreactivity

Increased airway smooth muscle (ASM) mass is believed to underlie the relatively fixed airway hyperresponsiveness (AHR) in asthma. Developments of therapeutic approaches to reverse airway remodeling are impeded by our lack of insight on the mechanisms behind the increase in mass of contractile ASM c...

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Vydáno v:FASEB J
Hlavní autoři: Tran, Thai, Teoh, Chun Ming, Tam, John Kit Chung, Qiao, Yongkang, Chin, Chin Yein, Chong, Oi Khuan, Stewart, Alastair G., Harris, Trudi, Wong, Wai Shiu Fred, Guan, Shou Ping, Leung, Bernard P., Gerthoffer, William T., Unruh, Helmut, Halayko, Andrew J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2013
Témata:
Research Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6159668/
https://ncbi.nlm.nih.gov/pubmed/23756649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-221341
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